Telnyx

10 best voice AI agents for healthcare in 2025

By Eli Mogul
10 Healthcare Voice AI agents

10 best voice AI agents for healthcare

Healthcare organizations face mounting pressure to deliver exceptional patient experiences while managing operational costs. Voice AI agents are gaining traction in healthcare. The market is expected to grow at a 37.79% CAGR between 2025 and 2030, according to Grand View Research. North America currently leads, accounting for 54.17% of global revenue.

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These intelligent systems handle everything from appointment scheduling to medication reminders, freeing clinical staff to focus on patient care. Healthcare providers implementing voice AI report reductions in missed appointments and increases in patient procedure preparation compliance, making these tools critical for both operational efficiency and clinical outcomes.

Why healthcare needs voice AI agents now

The healthcare industry operates in a uniquely challenging environment. Staffing shortages, growing administrative demands, and the need for round-the-clock patient communication have made traditional contact center models unsustainable. Voice AI agents address these challenges by providing instant, accurate responses to patient inquiries while integrating seamlessly with existing healthcare systems including EHR platforms

Healthcare providers report up to 70% reduction in administrative tasks with Voice AI, along with significant improvements in patient satisfaction rates. As demand for accessible, responsive care grows, AI-powered tools are becoming essential partners in modern healthcare delivery.

The top 10 voice AI agents for healthcare

1. Telnyx

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For healthcare organizations implementing voice AI, Telnyx offers several advantages:

Superior call quality: Our private IP network ensures medical conversations remain clear and professional, critical when discussing health information or providing care instructions.

EHR integrations: Telnyx's voice AI agents integrate directly with EHRs to streamline scheduling, documentation, and follow-ups.

Rapid deployment and migration: Launch new voice AI solutions in under 5 minutes with guided setup and 24/7 engineering support. Migrate from existing tools quickly and cost-effectively, minimizing disruption to patient care.

Global coverage with local presence: Licensed carrier in 30+ countries, and local numbers in 100+. Support for multilingual capabilities ensures healthcare organizations can serve diverse patient populations effectively

Security and compliance: End-to-end encryption, granular data controls, and detailed audit logs. We support BAAs and regional compliance needs out of the box.

Why Telnyx is better for healthcare:

Unlike “AI layer only” vendors, Telnyx combines reliable telephony infrastructure with real-time AI orchestration (STT/TTS + LLM streaming) on a private network reducing latency, jitter, and cost. You get one partner for numbers, calling, compliance, and AI call control, instead of managing multiple providers together. The result: better performance, simpler, compliant operations at scale and cost efficiency.

2. CloudTalk AI voice agents

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CloudTalk specializes in healthcare-specific use cases with its Alex AI Voice Agent. The platform handles everything from appointment scheduling to medication reminders, with seamless integration into existing healthcare workflows. CloudTalk's healthcare voice agents can handle appointment calls from start to finish, with virtual assistants managing phone lines so patients can book on their own terms.

The platform's strength lies in its ability to maintain conversational context across multiple interactions, ensuring patients never have to repeat information.

3. ElevenLabs

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ElevenLabs produces natural speech with rich emotion, multilingual support, and cloning for consistent brand delivery. It is well suited for pre op and post op instructions, medication education, and preventive care reminders across languages. Use ElevenLabs as the voice layer while Telnyx handles calling, routing, and compliance, or bring those voices into a complete Telnyx voice AI.

4. Hyro

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Hyro addresses complex patient journeys like intake, eligibility, directory navigation, and scheduling with enterprise integrations and multilingual support. Large systems can standardize quality and compliance by placing Hyro conversations on Telnyx numbers with real time media streaming.

5. Retell AI

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Retell AI stands out for its healthcare-ready infrastructure and rapid deployment capabilities.

The platform offers medical terminology ASR with ≥95% accuracy, multilingual TTS voices, and custom LLM support. Retell AI's drag-and-drop builder enables healthcare organizations to deploy voice agents within weeks, not months, while maintaining stringent security requirements.

6. Assort Health

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Assort Health delivers specialized AI solutions tailored by medical specialty.

Their voice AI agents excel at navigating complex scheduling algorithms across multiple providers and locations. In just 30 days, one orthopedic practice cut hold times from 11 minutes to 1 minute while booking more accurate appointments.

7. Zocdoc's Zo

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Zocdoc's AI voice agent Zo represents a significant shift in patient engagement strategy. Launched on May 1, Zo helps people book doctor appointments 24/7 through natural conversation with an AI voice trained to meet their specific needs.

The system features working memory capabilities, ensuring patients don't have to repeat information during conversations. Zo also had to be trained to understand "the cadence in which people speak with the specific idioms that they use", adapting to regional language differences across the United States.

8. Synthflow

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Synthflow offers a no-code platform for building healthcare voice agents. Healthcare companies can create custom AI phone call agents effortlessly with no coding or tech skills needed—just their data and ideas for powerful automation. As the call flows get complicated it might be difficult to manage.

9. PolyAI

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PolyAI specializes in enterprise healthcare deployments with multilingual capabilities. The platform creates lifelike voice assistants designed to understand callers naturally, enabling human-like interactions for large healthcare enterprises.

Their strength lies in handling high call volumes while maintaining conversation quality across multiple languages and dialects.

10. Callin.io

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Callin.io delivers healthcare-focused voice AI with impressive clinical outcomes.

The platform excels at post-visit follow-ups, medication adherence programs, and chronic disease management, with mental health practices reporting 47% better therapy homework completion when using Voice AI for between-session support.

Key features to consider

When evaluating voice AI agents for healthcare, several critical capabilities separate leading platforms from basic solutions:

Compliance and security: Look for platforms offering Business Associate Agreements (BAAs), end-to-end encryption, and comprehensive audit trails. The best solutions maintain SOC 2 Type 2 certification alongside HIPAA compliance.

EHR integration: Seamless connectivity with Epic, Cerner, Athena, and other major EHR systems ensures voice agents can access patient information and update records in real-time.

Medical terminology accuracy: Top platforms deliver ≥95% transcription accuracy across English, Spanish, French, Hindi, and Telugu, with emotion recognition hitting 88%.

24/7 availability: Voice agents that operate round-the-clock capture appointment requests when patient motivation strikes, not just during business hours.

Multilingual support: With diverse patient populations, voice agents must handle multiple languages and dialects while maintaining accuracy and cultural sensitivity.

Implementation considerations

Successfully deploying voice AI in healthcare requires careful planning and execution. Clinicians, nurses, front-desk staff, and care coordinators need to understand how these agents function, when to intervene, and how to override the system if necessary.

Start with high-volume, rule-based workflows like appointment scheduling or lab result notifications. These use cases deliver fast ROI with minimal risk. Gradually expand to more complex interactions as staff and patients become comfortable with the technology.

Consider beginning with a pilot program targeting specific patient populations or service lines. One approach is to start with employees or chronic-condition segments, gather feedback on voice tone and pacing, then gradually open the main line by rolling 25% of traffic each week while maintaining fallback to human agents.

Measuring success

Healthcare organizations implementing voice AI should track specific metrics to ensure positive outcomes:

Metric Typical improvement
Call abandonment rates 50-60% reduction
Average wait times From 11+ minutes to under 2 minutes
Patient satisfaction scores 85-90% approval ratings
Administrative cost savings $80,000-$100,000+ annual savings per eliminated FTE
No-show rates 25-35% reduction

How Telnyx enhances healthcare voice AI

While choosing the right voice AI agent is crucial, the underlying telephony infrastructure determines call quality and reliability. Telnyx owns its IP network and telephony stack, providing the ultra-low latency and crystal-clear call quality and carrier-grade reliability that healthcare communications demand. So critical calls connect, route, and escalate flawlessly across your workflows and patient-critical conversations never slip through the cracks.

Looking ahead

Generative AI voice agents are poised to transform how health systems engage with patients, expanding the reach of personalized, responsive communication in ways previously limited by human resources. As these technologies mature, we'll see even more sophisticated applications, from complex care coordination to real-time clinical decision support.

Healthcare organizations that invest in voice AI today position themselves for success in an increasingly digital healthcare landscape. The key is selecting platforms that balance advanced capabilities with ease of implementation, ensuring both staff and patients benefit from the technology.

Ready to explore how voice AI can transform your healthcare operations? Contact Telnyx to learn how our infrastructure can support your voice AI implementation with the reliability and compliance healthcare demands.

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